Almost happy
I don't have any specific route in mind but I think you should just go with the main upgrades and not many Missiles/Powerbombs/Supers since there is no boss that really needs a crapload of ammo. I don't know about E-tanks since there are a few places where you will need some, I guess you won't need to many though. Just try to keep away from pause abuse (except for when going to speedbooster since IIRC you won't do kraid first).
Screwattack early might save some time, especially when going for the first PBs since there are creatures there that take really much ammo to kill and needs to be killed.
Screwattack early might save some time, especially when going for the first PBs since there are creatures there that take really much ammo to kill and needs to be killed.